Glyceryl trinitrate and platelet aggregation: effects of N-acetyl- cysteine.
نویسندگان
چکیده
منابع مشابه
Inhibition of platelet aggregation by transdermal glyceryl trinitrate.
OBJECTIVE To determine the optimum conditions for the demonstration of an antiplatelet effect of nitric oxide and to use these conditions to elucidate the effects of a transdermal glyceryl trinitrate patch on platelet aggregation in normal volunteers. METHODS An open prospective crossover study. The effects of nitric oxide on platelet aggregation in whole blood and platelet rich plasma as sti...
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Xanthine oxidoreductase (XOR) is a mammalian enzyme that possesses a series of redox centers, which use either NAD(+) or molecular oxygen for oxidation of the purines xanthine and hypoxanthine to uric acid. The ability of XOR to act as an NADH oxidase is a less well recognized function of the enzyme, and it is this function that we used to explore the metabolism of glyceryl trinitrate. The anti...
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their interest in our article. First, we would like to apologize for mis-attributing the statement to the authors. The correct reference in our article was to 11 not 1 and it is not a direct quotation. We believe our survey provides sufficient evidence to raise concerns over the use of transtracheal ventilation using a high pressure source without control of airway pressure, but a survey lackin...
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The coronary haemodynamic effects of nifedipine and glyceryl trinitrate were compared in 22 patients undergoing investigations for suspected coronary artery disease. Myocardial blood flow was estimated by the coronary sinus thermodilution technique. In sinus rhythm nifedipine increased mean coronary sinus flow from 135 ml/min to 152 m/min, and reduced arterio-coronary sinus oxygen difference fr...
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Objective- Mechanisms that decrease oxidative stress and enhance peritoneal fibrinolysis reduce adhesions. N-acetyl-L-cysteine (NAC) is an antioxidant whose effect on peritoneal fibrinolysis in large animal model has not been established. The aims of this study were to investigate the ability of NAC to decreased adhesion in stablished model of serosal trauma in sheep. Design- Expe...
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ژورنال
عنوان ژورنال: British Journal of Clinical Pharmacology
سال: 1989
ISSN: 0306-5251
DOI: 10.1111/j.1365-2125.1989.tb03425.x